FAQ

How does the Oral Genome saliva testing work?

• Step 1: Collect your saliva sample in the morning.

• Step 2: Place your sample in the designated area of the test.

• Step 3: The test kit uses nano-bead antibody conjugates that bind to the antigens in your saliva, causing a color change. This reaction highlights specific markers that link your oral health to potential systemic conditions.

• Step 4: Take a photo of your test using the color-calibrated card. Oral Genome uses proprietary technology to match the colors produced by the reaction and how light travels through them to measure the levels of each antigen in your sample.

• Step 5: The app will return with your measurements and help you interpret what those levels mean for your wellness.

How accurate is the saliva test and how does it compare to common dental tests?

Very. In clinical testing, there are 2 key factors to determine a tests’ effectiveness: the sensitivity, the specificity. Oral Genome tests were rated 90% for sensitivity, 95% specificity.

For scale, in similar clinical tests, CAMBRA exams–commonly used in dental offices to assess your risk of future cavities–average 69% for sensitivity, and 53% for specificity.

What biomarkers does Oral Genome analyze, and how do they correlate with health?

Oral Genome analyzes key biomarkers in your saliva that offer a real-time look at your oral and overall health. These include:

• Salivary pH & buffering capacity – These are indicators of your mouth’s ability to prevent cavities and enamel erosion. Maintaining healthy levels here helps to fight decay and sensitivity.

• Porphyromonas Gingivalis (Pg) – Pg is a key bacteria linked to gum disease and systemic inflammation. Pg bacteria produce toxins generally linked to bone decay and bad breath, so it should be kept at very low levels.

• Matrix Metalloproteinase-8 (MMP-8) – MMP-8 is a biomarker that signals active tissue breakdown, which could be a warning sign for gum issues. Studies have also linked MMP-8 with tissue degradation in other parts of the body, including joints, bones, and organs.

• Nitric Oxide – Nitric oxide supports blood flow. Maintaining high levels can signal a healthy immune response.

• Glucose levels – Your glucose levels offer insight into metabolic health and can signal your potential diabetes risk.

• Salivary proteins – Reflecting immune function and oral microbiome balance.

By analyzing these markers, Oral Genome helps you take a data-driven approach to oral health—one that connects to longevity, metabolic wellness, and inflammation.

Is this test backed by peer-reviewed research or clinical studies?

• Yes. The Oral Genome saliva test is classified under the FDA's General Wellness: Policy for Low Risk Devices, ensuring it meets high safety and quality standards. You can review our research studies here.

How does Oral Genome compare to traditional dental exams and blood tests?

• Traditional dental exams and blood tests provide important check-ins, but they don’t always offer proactive, data-driven insights about your oral health and wellness.

Oral Genome saliva test doesn’t replace visits to your care team, but it is another tool in your wellness stack. Testing your saliva at home gives you personalized, science-backed information between visits—helping you stay ahead of potential issues like cavities, inflammation, diabetes, or metabolic risks.

With this data in hand, you can go into your next dental or medical appointment with specific, informed questions, optimizing your time with your healthcare team in-office.

How long does it take to get results from the at-home saliva test?

You can expect to receive your at-home saliva test results in just 15 minutes, providing quick and accurate insights into your oral health and overall wellness.

Can I track changes over time with the saliva test? How often should I retest?

Yes! We recommend testing every six months. Subtle changes in your biomarkers can signal when it’s time to adjust your routine or check in with your clinician. When it comes to your oral health, it’s more than just brushing and flossing™.

Is My data secure with Oral Genome? How is my health data stored?

• At Oral Genome, we prioritize healthcare data security and comply with all relevant data protection regulations, including HIPAA, to ensure your information remains safe.

Your health data is securely stored on protected servers and is accessible only to authorized personnel, held to the highest standards of confidentiality.

Rest assured, maintaining your privacy is our top priority.

Can I delete my data from Oral Genome if I choose to?

Yes. You can request your data be deleted by contacting us.

Is Oral Genome’s saliva test kit covered by FSA/HSA?

• Not at this time, but your wellness is worth the investment.

Will it save me money on dental care long-term by preventing issues early?

• Yes! By identifying early signs of cavities, gum disease, and metabolic risks, Oral Genome helps you take preventive action before small issues become expensive or painful dental procedures.

Proactive adjustments to your routine and care plan can reduce the need for costly treatments – like fillings, perioral cleanings, or gum surgery – in the future. Think of it as an investment in long-term health.